ketogenic diet

The ketogenic diet is a low carbohydrate limited , protein and calorie balance sheet and therefore the form of dietary -fat diet that mimics the starvation metabolism in certain aspects . In this type of diet the body gets its energy requirement is less fat and glucose but only fat and it built up in the body glucose replacement , the eponymous ketone bodies . A ketogenic diet is used as a method of therapy , especially in children with drug-resistant epilepsy , glucose transport disorder (eg, GLUT1 deficiency syndrome) and Pyruvatdehydrogenasemangel . You must be calculated individually and monitored by a physician . A non- medically induced special form of ketogenic diet are low-carb diets such as the Atkins diet.

effect

Proteins such as the various carbohydrates are converted into glucose to maintain blood sugar levels and thus to supply the brain with energy , especially in the metabolism approximately 50% and fats only about 10% ( ie their glycerol content ) . In the fasting state , the body starts by taking on its glycogen stores ( a storage form of carbohydrates ) back and then turns increasingly on a hunger metabolism to . This is characterized, inter alia , that fatty acids are broken down in the liver to ketone bodies , the energy needs, especially of the brain ( which is otherwise dependent on glucose as the sole energy source) then , to cover efficiently in an alternative way . The target state is called ketosis.

Calculation , implementation

For a ketogenic diet , the energy requirement ( 30-80 kcal / kg depending on age and metabolic rate ) is calculated and the protein requirement ( 0.7-2 g / kg depending on age) and then the " ketogenic ratio " (typically 3 - 4, 5: 1) fixed. The ketogenic ratio determines the weight ratio of fat to carbohydrates + proteins. A ketogenic ratio of 4:1, for example , that food to 80% by weight shall consist of fats. In the remaining 20 % by weight of the need for a comprehensive amount of protein must be accommodated. Accordingly, carbohydrates may be included only in minimal amounts to maintain an effective ketosis. A ketosis due to a random defect induced carbohydrate is broken by the addition of small amounts of excess carbohydrate in a short time, which can lead to increased seizures again . This strict diet regime requires careful indication, some detailed knowledge and a close cooperation between the treatment team and patients , their caregivers (eg parents) and their social environment . The diet prescription must be repeated adjusted by the doctor on the progress and identifiable needs. The proper implementation of the diet must be monitored via the urine and / or Blutketose (similar to blood glucose monitoring in Diabeteikern ) .

sources:

↑ from PR Huttenlocher , AJ Wilbourn , JM Signore : Medium - chain triglycerides as a therapy for intractable childhood epilepsy . In : Neurology. Hagerstown Md 21.1971,11 (Nov ) , 1097-1103 . PMID 5166216 ISSN 0028-3878
↑ EC Neal, Chaffe H , Schwartz RH , Lawson MS , Edwards N , among others : The ketogenic diet for the treatment of childhood epilepsy : a randomized controlled trial . In : The Lancet. Neurology. Oxford 7.2008,6 (Jun ) , 500-506 . doi: 10.1016/S1474-4422 (08) 70092-9 [Title based on this DOI to take in Citavi project] . PMID 18456557 ISSN 1474-4422
↑ JW . Wheless : History and origin of the ketogenic diet (PDF , 3.7 MB). In : Ernest Carl Stafstrom , Jong M Rho : Epilepsy and the ketogenic diet . Humana Press, Totowa , 2004. ISBN 1-58829-295-9 [ track with this ISBN take in Citavi project]
↑ " Despite its temporary side effects , we have always did the ketogenic diet is Suspected Relatively safe long term , and we now have proof . " In : High- Fat Ketogenic Diet to Control Seizures Is Safe Over Long-Term , Study Suggests . In : SienceDaily.com . Johns Hopkins Medical Institutions , February 17, 2010 , accessed March 4, 2011 (English) .
http://de.wikipedia.org/wiki/Ketogene_Di % C3 % 4t