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Glutamine takes on many tasks in the body
Regulate the balance between catabolism and anabolism
Regulation of cell volume
Formation of intestinal hormone Gucagonlike-Peptide-1
Metabolism of protein, fat and carbohydrates
Production of glutation (detoxified and antioxidant)
Production of purines and pyrimidines (building blocks of DNA and RNA)
Nitrogen transport and elimination of ammonia
Building material for proteins
Strengthening the immune system
Glutamine in sports
The muscle tissue is the largest glutamine producer of the body, whereby L-glutamine is at the same time the driving force behind the process of the muscle build-up. Of the approximately 20 different amino acids, glutamine is the most abundant and also the most frequently required amino acid in the muscle tissue. If glutamine is not present sufficiently, protein synthesis stops, i.e. No more protein is converted into muscle mass. During a strenuous physical training session, the situation may occur that the glutamine level drops very sharply. A few hours may pass before the glutamine level is increased again. Overtraining can have the result that the glutamine level does not recover completely. In the case of athletes who are permanently under constant stress, such as excessive training and dietary phases, the disturbance of the glutamine level may occur at times. It can thus be partially up to a yearly low glutamine level in the plasma
Deficiency of glutamine and the consequences
Even if glutamine is abundant in the body, a glutamine deficiency can develop and have serious consequences. Especially endurance athletes, e.g. Marathon runners are affected. This makes clear why a glutamine supplement is not only useful for bodybuilders who want to build muscle, but also for endurance athletes.
Consequences of glutamine deficiency
Reduction of the quality and function of the intestinal epithelium
Increase the risk of infections and allergies
Deceleration of wound healing
How necessary is glutamine
Although healthy people themselves form enough glutamine, there are situations where L-glutamine becomes an essential amino acid. Especially in the case of severe stress, such as illness, stress or sport. The muscles release the stored L-glutamine to be used in the body where it is needed. If the load is too long, the glutamine levels in the muscles are restored. If the stress phases are long-lasting, the demand for L-glutamine is particularly high. If L-glutamine is not present sufficiently, the muscles can be damaged or an immune deficiency can occur. Especially in stressful situations or in the case of malnutrition as in a diet, the glutamine intake in the small intestine can radically decrease.
Difference of glutamine and glutamate
Some people know it, the so-called Chinarestaurant syndrome. After an extensive meal with the Chinese, you sink into a deep full of fatigue to headaches. There are people who seem to be overly sensitive to glutamate. Glutamate is the sodium salt of glutamic acid and is used as a taste enhancer for many pastry dishes, sauces and meals. Importantly, glutamate is not confused with the amino acid L-glutamine.